treated with diagnosed using measurement in guideline Serum Creatinine Level Acute Tubular Necrosis Renal Tubular Necrosis Loss of kidney function, reduced urine output, elevated serum creatinine. Renal ischemia (which can occur due to prolonged prerenal states), nephrotoxins, or sepsis. In sickle cell disease, may occur due to renal ischemia related to sickle crisis. Provide source for additional info. HP:0008682 The clinical course of acute tubular necrosis may be divided into initiation, maintenance, and recovery phases. SCDO:0000020 Acute death of renal tubular cells that usually results from prolonged renal ischemia, nephrotoxins, or sepsis. Sufficient Can occur at any age. ATN Renal Dialysis Supportive Therapeutics Acute Phenotype A Parental Guide to Managing Sickle Cell Disease