treated with in guideline Abnormality of the Skeletal System Increased Bone Mineral Density An increased whiteness (density) of affected bones. An abnormal increase of bone mineral density, that is, of the amount of matter per cubic centimeter of bones which is often refered to as osteosclerosis. Osteosclerosis can be detected on radiological examination as an increased whiteness (density) of affected bones. Osteosclerosis HP:0011001 Provide source for additional info. Osteosclerosis of Bones Increased Bone Density Sufficient Bone Sclerosis http://purl.obolibrary.org/obo/HP_0011001 Ischemia, chronic infection, and tumor formation, osteoarthritis, osteoma, hepatitis C, . May be caused by faulty bone resorption as a result of some abnormality involving osteoclasts. SCDO:0000629 Treatment of Precipitating Factors Recommendations for the Management of Sickle Cell Disease in South Africa National Guideline for the Control and Management of Sickle Cell Disease Evidence-Based Management of Sickle Cell Disease