diagnosed using tool has mode of inheritance has causal genotype High-Performance Liquid Chromatography Autosomal Recessive Hemoglobin Lepore Syndrome NCIT:C141366 Homozygous Hb Lepore A rare autosomal recessive hemoglobinopathy, caused by the presence of two deltabeta globin fusion chains, which occurs due to a crossover between the delta (HBD) and beta globin (HBB) gene loci during meiosis. http://en.wikipedia.org/wiki/Hemoglobin_Lepore_syndrome Hb Lepore Syndrome Sufficient Homozygous Hemoglobin Lepore Hb Lepore SCDO:0000538 Genetic Testing Delta Beta Thalassemia Isoelectric Focusing Crossover between delta (HBD) and beta globin (HBB) gene loci