modifies Mutation Deletion Mutation Deletion Abnormality NCIT:C19296 SCDO:0001371 Any rearrangement to the genomic content that results in the loss of one or more nucleotides of DNA. Deletions are generally irreversible rearrangements. They may alter the reading frame of a gene, or may result in loss of large chromosomal regions. Sufficient http://purl.obolibrary.org/obo/NCIT_C19296 Gene Product