in guideline Abnormality of the Respiratory System Hypoxia A decrease in the amount of oxygen in the body. Symptoms range from mild (impaired judgment, memory loss, impaired motor coordination) to severe (seizures and coma). In SCD patients, this is considered as saturated oxygen < 95% on air. Have merged the definition of hypoxia from NCIT and the Tanzanian Management Guidelines. Not sure if the SaO2 value is specific to SCD patients - please get a clinician to review. This is a symptom of acute chest syndrome. NCIT:C3890 SCDO:0004183 SCD Management guidelines - Tanzania Sufficient Recommendations for the Management of Sickle Cell Disease in South Africa National Guideline for the Control and Management of Sickle Cell Disease Management of Sickle Cell Disease - The United Republic of Tanzania Standards for Clinical Care of Adults with Sickle Cell Disease in the UK Sickle Cell Disease: The Clinical Care Guidelines of the Sickle Cell Unit Consensus Statement on the Care of Patients with Sickle Cell Disease in Canada Sickle Cell Disease in Children, Standards and Guidelines for Clinic Care Evidence-Based Management of Sickle Cell Disease Management of Children with Sickle Cell Disease in Europe: Current Situation and Future Perspectives ENERCA Clinical Recommendations for Disease Management and Prevention of Complications of Sickle Cell Disease in Children