diagnosed using tool has manifestation Diabetes Mellitus Hypothyroidism Delayed Puberty Osteoporosis Cholelithiasis Splenomegaly Anemia Frontal Bossing Hypoxemia Infection Increased Susceptibility to Bacterial Infection Genetic Testing Bacterial Infection Viral Infection Iron Overload Blood Smear Beta Thalassemia Major Beta-Thalassemia Major Cooley's Anemia A severe early-onset form of beta thalassemia characterized by severe anemia requiring regular red blood cell transfusions. Cooley Anemia Sufficient Mediterranean Anemia SCDO:0000113 BT Major B0/B0 ORPHA:231214 Thalassemia Major Clinical Phenotype of Beta Thalassemia Growth Delay Hemoglobin Profile Assay Leg Ulcer Pulmonary Hypertension Chronic Anemia Hypersplenism