treats in guideline Acute Chest Syndrome Severe Anemia Nephropathy Hydrops Fetalis Impaired Renal Concentrating Ability Sickle Cell Disease-SD Sickle Cell Chronic Lung Disease Postpartum Hemorrhage Hemoglobin H Disease Sickle Cell Disease-S Beta Zero Thalassemia Blood Transfusion The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed) Sufficient The major and unavoidable complication of transfusions in sickle cell disease is iron overload. Transfusion is well-defined as prophylaxis (stroke) and as therapy (acute chest syndrome and stroke) for major complications of sickle cell disease and has been instituted, based on less conclusive data, for a range of additional complications, such as priapism, vaso-occlusive crises, leg ulcers, pulmonary hypertension, and during complicated pregnancies. http://purl.bioontology.org/ontology/MESH/D001803 SCDO:0000147 Blood Transfusions MESH:D001803 Radha Raghupathy, Deepa Manwani, and Jane A. Little, “Iron Overload in Sickle Cell Disease,” Advances in Hematology, vol. 2010, Article ID 272940, 9 pages, 2010. doi:10.1155/2010/272940 Hemoglobin C Disease Hemoglobin E Disease Non-specific Acute Lower Respiratory Tract Episode Preventative Therapeutics Recurrent Wheeze in Sickle Cell Disease Sickle Cell Disease-S/O-Arab Symptomatic Therapeutics Moderate Sickle Cell Disease-S Beta Minus Thalassemia Severe Sickle Cell Disease-S Beta Minus Thalassemia Recommendations for the Management of Sickle Cell Disease in South Africa National Guideline for the Control and Management of Sickle Cell Disease Management of Sickle Cell Disease - The United Republic of Tanzania A Parental Guide to Managing Sickle Cell Disease Standards for Clinical Care of Adults with Sickle Cell Disease in the UK Sickle Cell Disease: The Clinical Care Guidelines of the Sickle Cell Unit Consensus Statement on the Care of Patients with Sickle Cell Disease in Canada Sickle Cell Disease in Children, Standards and Guidelines for Clinic Care Evidence-Based Management of Sickle Cell Disease Management of Children with Sickle Cell Disease in Europe: Current Situation and Future Perspectives ENERCA Clinical Recommendations for Disease Management and Prevention of Complications of Sickle Cell Disease in Children