treated with in guideline Amitriptyline Pregabalin Chronic Neuropathic Pain Few but definitions not freely available Chronic pain caused by damage to nerve fibers. It is usually associated with tissue injury. This pain is usually described as burning, numb, tingling, lancinating, shooting, or paroxysmal in nature and is associated with a sensation of pins and needles. Its severity is also enhanced by exposure to either cold or heat. Evidence-Based Management of Sickle Cell Disease: Expert Panel Report (EPR), 2014 Request inclusion into relevant ontology Chronic Sickle Cell Pain Management of Sickle Cell Disease - The United Republic of Tanzania Standards for Clinical Care of Adults with Sickle Cell Disease in the UK Sickle Cell Disease: The Clinical Care Guidelines of the Sickle Cell Unit Consensus Statement on the Care of Patients with Sickle Cell Disease in Canada Evidence-Based Management of Sickle Cell Disease