in guideline Viral Infection Dengue Fever Breakbone Fever Break-Bone fever http://purl.bioontology.org/ontology/MESH/D003715 Dengue SCDO:0000346 MESH:D003715 Break Bone Fever Sufficient An acute febrile disease transmitted by the bite of AEDES mosquitoes infected with Dengue Virus. It is self-limiting and characterized by fever, myalgia, headache, and rash. Severe Dengue is a more virulent form of dengue. Sickle Cell Disease: The Clinical Care Guidelines of the Sickle Cell Unit