diagnosed using tool treated with has mode of inheritance has causal genotype has causal or contributing genetic variation has manifestation has causal molecular phenotype High-Performance Liquid Chromatography Complete Blood Count Splenomegaly Hemolytic Anemia Blood Smear Blood Transfusion Electrophoresis Hematopoietic Stem Cell Transplantation Hemoglobin C Hemoglobin C Disease NCIT:C34675 Suggest update to description Hb C-Disease Haemoglobin C Disease http://newbornscreeningcodes.nlm.nih.gov/nb/sc/condition/Hb-F-C An autosomal recessive disorder resulting from the production of hemoglobin C, secondary to an amino acid substitution of lysine for glutamic acid in the sixth position of the beta chain (E6K), and characterized by mild hemolytic anemia and occasionally jaundice, though most patients are asymptomatic. Suggest update to description in NCIT Hydroxyurea Folic Acid Structural Hemoglobinopathy HBB, GLU6LYS Hemoglobin Genotype CC Autosomal Recessive Homozygous