has mode of inheritance has causal genotype has causal or contributing genetic variation has causal molecular phenotype Autosomal Recessive Hemoglobin D Disease Suggest update to description in ORDO DOID:5378 Homozygous Hemoglobin D Hb DD http://www.doh.wa.gov/Portals/1/Documents/5220/HbDFactSheet.pdf An autosomal recessive hemoglobinopathy characterized by production of abnormal variant hemoglobin known as hemoglobin D, with no or mild clinical manifestations (splenomegaly, very mild anemia). Suggest update to description Structural Hemoglobinopathy Hemoglobin D HBB, SER9TYR HBB, GLU121GLN HBB, GLY16ARG HBB, ASN19LYS HBB, GLU22GLN HBB, GLU22VAL HBB, THR87LYS HBB, GLU121ALA Hemoglobin Genotype DD