Abnormal Nervous System Physiology Neurocognitive Impairment SCDO None Request inclusion into relevant ontology An invisible complication of sickle cell anemia (SSA) that defies detection by imaging and other routine diagnostic methods. Impaired neurocognitive function in seemingly neurologically intact patients is not related to vasoocclusion or hemolysis. It is detected by neuropsychiatric and neurobehavioral testing and is associated with anemia and age. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415156/ Phenotype of Sickle Cell Disease