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    <!-- http://purl.obolibrary.org/obo/SCDO_0001297 -->

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        <rdfs:label>has essential measure</rdfs:label>
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        <rdfs:label>measures</rdfs:label>
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        <rdfs:label>in guideline</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CMO_0000003 -->

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        <rdfs:label>Blood Pressure Measurement</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/NCIT_C17241 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C17241">
        <rdfs:label>Urine Test</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/NCIT_C17357 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C17357">
        <rdfs:label>Gender</rdfs:label>
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        <rdfs:label>Current Age</rdfs:label>
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        <rdfs:label>History of Kidney Failure Diagnostic Instrument</rdfs:label>
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        <rdfs:label>History of Type I and Type 2 Diabetes Diagnostic Instrument</rdfs:label>
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        <rdfs:label>Kidney Function Test</rdfs:label>
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        <rdfs:label>Urinary Albumin Test</rdfs:label>
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        <obo:SCDO_0000303>Label different from source&#39;s &quot;Urinary Microalbumin - Assay&quot;</obo:SCDO_0000303>
        <rdfs:comment>In the protocol provided, albumin concentration is measured according to a fluorescent immunoassay (FIA). The protocol also lists reference ranges for healthy adults.

The criteria for clinically significant proteinuria have been changed from an albumin-creatinine ratio (ACR) of 30 mg/mmol or more to 3 mg/mmol or more. This is because there is evidence that the risk of adverse outcomes is a continuum and starts at an ACR well below 30 mg/mmol.

The Sickle Cell Disease Research and Scientific Panel notes that the terms &quot;microalbuminuria&quot; and &quot;macroalbuminuria&quot; have been used clinically to describe different levels of abnormal albumin excretion rate: 30-299 mg/g urine creatinine, and &gt;300 mg/gr urine creatinine, for microalbuminuria and macroalbuminuria, respectively. Recently, a new terminology has been proposed: &quot;low level albuminuria&quot; instead of microalbuminuia, and &quot;high level albuminuria&quot; for macroalbuminuria, since the older terminology could be interpreted as measuring different molecular forms of albumin. 

Because albuminuria may be affected by non-pathological factors (exercise, menstruation contamination, biological variability, etc.), abnormal values should be confirmed within 1-2 months.</rdfs:comment>
        <obo:SCDO_0000479>PhenX protocol: Urinary Microalbumin Assay #141501</obo:SCDO_0000479>
        <obo:SCDO_1000288>Suggest update to label</obo:SCDO_1000288>
        <obo:IAO_0000115>A bioassay to measure urine concentration of albumin, which is produced by the liver and is the most abundant protein in the blood.</obo:IAO_0000115>
        <dc:source rdf:resource="http://patient.info/doctor/microalbuminuria"/>
        <obo:SCDO_0000340 rdf:resource="https://www.phenxtoolkit.org/protocols/view/141501"/>
        <obo:SCDO_0000479 rdf:resource="https://wwwn.cdc.gov/nchs/data/nhanes/2017-2018/labmethods/ALB-CR-J-MET-Urine-Albumin-508.pdf"/>
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    <!-- http://purl.obolibrary.org/obo/SCDO_0001209 -->

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        <rdfs:label>Urine Albumin Concentration</rdfs:label>
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        <rdfs:label>Recommendations for the Management of Sickle Cell Disease in South Africa</rdfs:label>
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        <rdfs:label>Standards for Clinical Care of Adults with Sickle Cell Disease in the UK</rdfs:label>
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