diagnosed using tool Personal Medical History Bronchodilator Responsiveness Test Phenotype of Sickle Cell Disease Physical Examination Pulmonary Function Test Wheezing Episode with Co-Morbid Asthma Paediatr Respir Rev. 2014 Mar;15(1):13-6. doi: 10.1016/j.prrv.2013.10.005. Epub 2013 Oct 31. None Increased severity of episodes. Glassberg, Jeffrey A., Robert Strunk, and Michael R. DeBaun. “Wheezing in Children with Sickle Cell Disease.” Current opinion in pediatrics 26.1 (2014): 9–18. PMC. Web. 2 Aug. 2017. An acute onset of wheezing in a person with SCD and co-morbid asthma. Glassberg, Jeffrey A., Robert Strunk, and Michael R. DeBaun. “Wheezing in Children with Sickle Cell Disease.” Current opinion in pediatrics 26.1 (2014): 9–18. PMC. Web. 2 Aug. 2017. Paediatr Respir Rev. 2014 Mar;15(1):13-6. doi: 10.1016/j.prrv.2013.10.005. Epub 2013 Oct 31. Asthma Attack SCDO Synergistic inflammatory response due to both SCD and asthma.