in guideline Chronic Phenotype Chronic Hypersplenism Chronic splenic sequestration associated with enlarged spleen and cytopaenia with anaemia and reduction in white blood cells and platelets. The anaemia is usually chronic in nature and patients rarely present with signs of heart failure. SCDO None Management of Sickle Cell Disease - The United Republic of Tanzania (By Ministry of Health) Request inclusion into the HPO below "Hypersplenism". Hypersplenism Management of Sickle Cell Disease - The United Republic of Tanzania Sickle Cell Disease: The Clinical Care Guidelines of the Sickle Cell Unit