has causal or contributing genetic variation Abnormal Hemoglobin in SCD Abnormal Hemoglobin Hemoglobin E MESH:D006446 Sufficient SCDO:1000009 An abnormal hemoglobin that results from the substitution of lysine for glutamic acid at position 26 of the beta chain. It is most frequently observed in southeast Asian populations. Request inclusion in the HPO, below "Abnormal Hemoglobin", for the sake of completion. http://purl.bioontology.org/ontology/MESH/D006446 Hb E HBB, GLU26LYS