causes or contributes to condition contributes to genotype causes or contributes to molecular phenotype Hemoglobin E Trait Sickle Cell Disease-SE Beta-Minus Thalassemia Mutation Other HBB Variants Hemoglobin E HBB, GLU26LYS Beta E Mutation SCDO (Jade Hotchkiss) HbE Mutation Negligable Request inclusion into relevant ontology A mutation in the HBB gene causing substitution of glutamic acid for lysine at the 26th position of the beta-globin chain. Hemoglobin Genotype SE Hemoglobin Genotype AE Hemoglobin Genotype EE