causes condition has contributing genetic variation causes molecular phenotype HBB, GLU6VAL HBB, LEU68PHE SCD Genotype Hemoglobin Genotype A/Jamaica Plain A/Jamaica Plain Haemoglobin Genotype A genotype that involves a double mutation in one beta-globin gene that results in hemoglobin with low oxygen affinity, which results in the polymerisation of the hemoglobin variant (hemoglobin Jamaica Plain) and thus sickling of erythorcytes. Haemoglobin Genotype A/Jamaica Plain Request inclusion into relevant ontology A/Jamaica Plain Genotype A/Jamaica Plain Hemoglobin Genotype None http://ac.els-cdn.com/S014067361061029X/1-s2.0-S014067361061029X-main.pdf?_tid=691c25c0-5826-11e7-b704-00000aacb35e&acdnat=1498230953_4d1264c47385275daf8fc2a1e1de62e3 Hemoglobin Jamaica Plain Sickle Cell Disease A/Jamaica Plain