causes condition has contributing genetic variation causes molecular phenotype Hemoglobin E Trait Genotype Hemoglobin E HBB, GLU26LYS Hemoglobin Genotype AE None Request inclusion into relevant ontology beta / beta26Glu>Lys SCDO (Clair Ingram) AE Genotype Haemoglobin Genotype AE Hemoglobin E Trait Genotype AE Hemoglobin Genotype A genotype whereby one HBB allele produces hemoglobin beta chains for normal adult hemoglobin and the other produces the abnormal hemoglobin beta chains for hemoglobin E. Individuals with this genotype are known to be carriers of the hemoglobin E trait.