concretizes is about is_about created_by date entity generically dependent continuant information representation information information content entity 1 ICEs are abstract entities that convey information about things in the world. ICEs represent the information encoded in physical artifacts such as photographs, books, or digital storage medium (as opposed to the physical medium itself). A particular ICE can be encoded simultaneously in many physical or digital mediums and formats. For example, only one instance of the first edition of "War and Peace" exists as an ICE, representing information conveyed in this work. But many instances of "War and Peace" exist at the level of their physical concretizations in printed books or digital devices. A generically dependent continuant that is about some thing. Pier: 'data, information or knowledge'. OR 'representation - Data Items: A '548.5 mg/dl' measurement of blood glucose in mutant mice. - Protocols: A blood glucose assay protocol that describes how the measurement was taken. - Calculations: A 1.3951e-24 p-value statistic indicating a significant increase relative to wild-type mice. - Assertions: An assertion stating that "Lpr1 leptin receptor mutations can lead to diabetes". - Publications: A journal article that publishes this assertion. - Figure/Tables: A figure or table from this article that present data supporting it. - Software/Algorithms: A text-mining algorithm that mines the literature to identify and extract the assertion. - Databases: The MGI (Mouse Genome Informatics) database that stores the assertion as a structured gene-disease annotation. information content entity Agent