non_functional_homolog_of pseudogene INSDC_qualifier:unknown A sequence that closely resembles a known functional gene, at another locus within a genome, that is non-functional as a consequence of (usually several) mutations that prevent either its transcription or translation (or both). In general, pseudogenes result from either reverse transcription of a transcript of their "normal" paralog (SO:0000043) (in which case the pseudogene typically lacks introns and includes a poly(A) tail) or from recombination (SO:0000044) (in which case the pseudogene is typically a tandem duplication of its "normal" paralog). INSDC_feature:gene SO:0000336 sequence INSDC_qualifier:pseudo http://en.wikipedia.org/wiki/Pseudogene gene biological_region