coding_sequence_variant initiator_codon_variant snpEff:NON_SYNONYMOUS_START SO:0001582 This is being used to annotate changes to the first codon of a transcript, when the first annotated codon is not to methionine. A variant is predicted to change the first amino acid of a translation irrespective of the fact that the underlying codon is an AUG. As such for transcripts with an incomplete CDS (sequence does not start with an AUG), it is still called. loinc:LA6695-6 initiator codon change kareneilbeck VAT:startOverlap A codon variant that changes at least one base of the first codon of a transcript. http://snpeff.sourceforge.net/SnpEff_manual.html initiatior codon variant 2010-03-22T02:35:18Z sequence http://vat.gersteinlab.org/formats.php Jannovar:initiator_codon_variant