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    <!-- http://purl.obolibrary.org/obo/SO_0001580 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SO_0001580">
        <rdfs:label>coding_sequence_variant</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SO_0001819 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SO_0001819">
        <rdfs:label>synonymous_variant</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/SO_0001580"/>
        <oboInOwl:hasRelatedSynonym>silent_mutation</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasOBONamespace>sequence</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym>Jannovar:synonymous_variant</oboInOwl:hasExactSynonym>
        <oboInOwl:id>SO:0001819</oboInOwl:id>
        <oboInOwl:hasAlternativeId>SO:0001588</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym>synonymous_codon</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>snpEff:SYNONYMOUS_CODING</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>http://en.wikipedia.org/wiki/Silent_mutation</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>VAAST:synonymous_variant</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>http://snp.gs.washington.edu/SeattleSeqAnnotation137/HelpHowToUse.jsp</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>ANNOVAR:synonymous SNV</oboInOwl:hasRelatedSynonym>
        <rdfs:comment>EBI term: Synonymous SNPs - In coding sequence, not resulting in an amino acid change (i.e. silent mutation).
This term is sometimes used synonomously with the more general term &#39;silent mutation&#39;, although a silent mutation may occur in non coding sequence. The best practice is to annotate to the most specific term.</rdfs:comment>
        <oboInOwl:hasExactSynonym>VAAST:synonymous_codon</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>http:www.ensembl.org/info/genome/variation/predicted_data.html#consequences</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Seattleseq:synonymous</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>http://snpeff.sourceforge.net/SnpEff_manual.html</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>coding-synon</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>silent substitution</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>http://vat.gersteinlab.org/formats.php</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Seattleseq:synonymous-near-splice</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>VAT:synonymous</oboInOwl:hasExactSynonym>
        <oboInOwl:creation_date>2011-06-24T03:38:30Z</oboInOwl:creation_date>
        <oboInOwl:hasExactSynonym>synonymous_coding</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>synonymous codon</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>http://en.wikipedia.org/wiki/Synonymous_mutation</oboInOwl:hasDbXref>
        <oboInOwl:created_by>kareneilbeck</oboInOwl:created_by>
        <ns3:IAO_0000115>A sequence variant where there is no resulting change to the encoded amino acid.</ns3:IAO_0000115>
        <oboInOwl:hasRelatedSynonym>silent mutation</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>VEP:synonymous_variant</oboInOwl:hasExactSynonym>
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