functional_effect_variant altered_gene_product_level SO:0002314 Added as per request from Ang Roberts as part of GenCC November 2020. See Issue Request #501 (https://github.com/The-Sequence-Ontology/SO-Ontologies/issues/501). Updated definition 17 Feb 2023 along with updates from GenCC. See Issue Request #612. altered gene product level sequence altered transcription level david 2020-12-18T22:35:30Z altered_transcription_level A sequence variant that alters the level or amount of gene product produced. This high level term can be applied where the direction of level change (increased vs decreased gene product level) is unknown or not confirmed.