statistic area under curve Orlaith Burke Alejandra Gonzalez-Beltran PMID:12892658 "Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change." PRS: submit 'integral calculus' as a kind of data transformation in OBI:DT branch Philippe Rocca-Serra area under curve is a measurement datum which corresponds to the surface define by the x-axis and bound by the line graph represented in a 2 dimensional plot resulting from an integration or integrative calculus. The interpretation of this measurement datum depends on the variables plotted in the graph ready for release