has specified data input has specified data output implements has format specification is executed in data item data format specification LPE Nandini Badarinarayan This LPE library is used to do significance analysis of microarray data with small number of replicates. It uses resampling based FDR adjustment, and gives less conservative results than traditional 'BH' or 'BY' procedures. Data accepted is raw data in txt format from MAS4, MAS5 or dChip. Data can also be supplied after normalization. LPE library is primarily used for analyzing data between two conditions. To use it for paired data, see LPEP library. For using LPE in multiple conditions, use HEM library. http://bioconductor.org/packages/2.4/bioc/html/LPE.html R data frame Gene expression dataset Local-pooled-error R software 'FDR' data normalization descriptive statistical calculation differential expression analysis