symptom skin and integumentary tissue symptom symptoms UMLS_CUI:C0159037 A skin and integumentary tissue symptom that is characterized by the outer layer of the skin starting to replace itself. Often, this happens when skin is damaged, either by disease or injury. UMLS_ICD9CM_2005_AUI:A0284146 ICD9CM_2005:782 ICD9CM_2005:782.9 UMLS_ICD9CM_2005_AUI:A0284161 SYMP:0000488