beta-Sheet binding to DNA TATA-binding proteins CLASSLINK:http\://www.edgar-wingender.de/class 8.1.html Class Class description: A 10-stranded, anti-parallel beta-sheet forms a quasi-symmetric saddle-like structure, where the convex side is backed by four alpha-helices and the concave side exerts mostly hydrophobic interactions with the minor groove of the TATA-box. Binding of TBP imposes a significant kink of the DNA double helix axis. (PMID 10617571, and references cited therein)