part_of part of part of signaling receptor binding signal transduction signaling receptor activator activity receptor ligand activity agonist signaling receptor ligand activity signaling molecule The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same cell that expresses the receptor. Ligands may also be expressed at the plasma membrane of an adjacent cell (e.g. Notch ligands) or be secreted and diffuse extracellularly from their point of origin to the receiving cell (e.g. interleukins). receptor agonist activity