has role has attribute value has attribute zileuton (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma. CAS:111406-87-2 CHEBI:10112 DrugBank:DB00744 Drug_Central:2862 LINCS:LSM-5084 Leutrol N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea PMID:19309543 PMID:19645854 PMID:20204486 PMID:20436887 Zileuton Zyflo zileuton zileutonum non-steroidal anti-inflammatory drug leukotriene antagonist anti-asthmatic drug organic molecular entity EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor drug liver toxicity Most-DILI-Concern