has role has attribute value has attribute alkylating agent busulfan 1,4-Bis(methanesulfonoxy)butane 1,4-Butanediol dimethanesulfonate 1,4-Dimesyloxybutane 1,4-Dimethanesulfonoxybutane A methanesulfonate ester that is butane-1,4-diol in which the hydrogens of the hydroxy groups are replaced by methanesulfonyl groups. An alkylating antineoplastic agent, it is used for the treatment of chronic myeloid leukemia (although it has been largely replaced by newer drugs). It is also used as an insect sterilant. Beilstein:1791786 Bisulfex Busulfan CAS:55-98-1 CHEBI:28901 DrugBank:DB01008 Drug_Central:438 LINCS:LSM-5388 Leucosulfan Mablin Mielucin Misulban Mitostan Myeloleukon Myleran PMID:10523796 PMID:19361744 PMID:19611402 Reaxys:1791786 Tetramethylene bis(methanesulfonate) busulfan busulfano busulfanum butane-1,4-diyl dimethanesulfonate antineoplastic agent organic molecular entity carcinogenic agent teratogenic agent insect sterilant drug liver toxicity Most-DILI-Concern