has role has attribute value has attribute azathioprine 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. CAS:446-86-6 CHEBI:2948 DrugBank:DB00993 Drug_Central:269 Imuran (TN) PMID:11064448 PMID:15199672 PMID:15476481 PMID:15628319 PMID:15973722 PMID:16344342 PMID:16397313 PMID:16764353 PMID:16954801 PMID:17381669 PMID:17970886 PMID:18008354 PMID:18336531 PMID:19243907 PMID:20080917 PMID:25248004 PMID:25314066 PMID:25440430 PMID:25443086 PMID:25581826 PMID:25641386 PMID:28166217 PMID:8738760 PMID:9273463 PMID:9345422 Reaxys:1225351 antimetabolite antineoplastic agent immunosuppressive agent prodrug organic molecular entity carcinogenic agent hepatotoxic agent DNA synthesis inhibitor drug liver toxicity Most-DILI-Concern