has role has attribute value has attribute antiviral drug abacavir A 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection. ABC Abacavir Beilstein:7493116 CAS:136470-78-5 CHEBI:421707 DrugBank:DB01048 Drug_Central:34 PMID:11678376 PMID:11806176 PMID:12781181 PMID:15887959 PMID:16458506 PMID:16539393 PMID:16759112 PMID:17172311 PMID:17870541 PMID:18029175 PMID:18549801 PMID:24751900 PMID:25017682 PMID:25674793 PMID:26024233 Reaxys:7493116 abacavir {(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol organic molecular entity HIV-1 reverse transcriptase inhibitor drug allergen drug liver toxicity Most-DILI-Concern