has role has attribute value has attribute alkylating agent antineoplastic agent dacarbazine 4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide 4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide 4-(dimethyltriazeno)imidazole-5-carboxamide 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide 5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide 5-(3,3-dimethyltriazeno)imidazole-4-carboxamide 5-(dimethyltriazeno)imidazole-4-carboxamide A monocarboxylic acid amide that is 1H-imidazole-4-carboxamide which is substituted at position 5 by a 3,3-dimethyltriaz-1-en-1-yl group. It is used for the treatment of metastatic malignant melanoma, and in combination with other drugs for the treatment of Hodgkin's disease and soft-tissue sarcoma. Beilstein:521487 CAS:4342-03-4 CHEBI:4305 DIC DTIC Di-me-triazenoimidazolecarboxamide DrugBank:DB00851 Drug_Central:773 Dtic-Dome (TN) HSDB 3219 ICDMT Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)- NCI-C04717 NSC 45388 NSC-45388 PMID:10751609 PMID:11318431 PMID:12195827 PMID:15010317 PMID:20082117 PMID:21471822 PMID:21654834 PMID:23029050 PMID:23318786 PMID:26940170 PMID:28096700 PMID:28250333 PMID:28387914 PMID:28419676 PMID:29076951 PMID:29184162 PMID:29287706 PMID:29296081 PMID:29305638 PMID:29344241 Reaxys:521487 dacarbazina dacarbazine dacarbazinum deticene prodrug organic molecular entity carcinogenic agent drug liver toxicity Most-DILI-Concern