has role has attribute value has attribute antimetabolite antineoplastic agent hydroxyurea A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease. Beilstein:1741548 CAS:127-07-1 CHEBI:44423 DrugBank:DB01005 Drug_Central:1399 Gmelin:130423 Hydroxycarbamid Hydroxycarbamide Hydroxyharnstoff Hydroxyurea N-HYDROXYUREA N-carbamoylhydroxylamine N-hydroxyurea PMID:11285159 PMID:11298103 PMID:11364534 PMID:11365149 PMID:11391710 PMID:12107454 PMID:14988684 PMID:15772364 PMID:15994344 PMID:16356682 PMID:22983419 PMID:23318979 PMID:23643402 PMID:23696560 PMID:9271088 Reaxys:1741548 carbamohydroxamic acid carbamohydroximic acid carbamoyl oxime carbamyl hydroxamate hidroxicarbamida hydrea hydroxycarbamide hydroxycarbamidum hydroxyurea oxyurea radical scavenger immunomodulator organic molecular entity genotoxin teratogenic agent DNA synthesis inhibitor antimitotic EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor drug liver toxicity Most-DILI-Concern