has role has attribute value has attribute antineoplastic agent gefitinib 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline A member of the class of quinazolines that is quinazoline which is substituted by a (3-chloro-4-fluorophenyl)nitrilo group, 3-(morpholin-4-yl)propoxy group and a methoxy group at positions 4,6 and 7, respectively. An EGFR kinase inhibitor used for the treatment of non-small cell lung cancer. CAS:184475-35-2 CHEBI:49668 DrugBank:DB00317 Drug_Central:1282 Iressa Irressat LINCS:LSM-1098 N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine PMID:14981586 PMID:15068398 PMID:20573926 PMID:20949670 PMID:27396387 PMID:28968167 PMID:29332330 PMID:29493460 PMID:29579334 PMID:29668619 PMID:30068310 PMID:30069771 PMID:30214852 Reaxys:8949523 ZD 1839 ZD-1839 ZD1839 gefitinib gefitinibum organic molecular entity epidermal growth factor receptor antagonist drug liver toxicity Most-DILI-Concern