has role has attribute value has attribute antineoplastic agent antiviral drug tyrosine kinase inhibitor angiogenesis inhibitor organic molecular entity sorafenib 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide A member of the class of phenylureas that is urea in which one of the nitrogens is substituted by a 4-chloro-3-trifluorophenyl group while the other is substituted by a phenyl group which, in turn, is substituted at the para position by a [2-(methylcarbamoyl)pyridin-4-yl]oxy group. CAS:284461-73-0 CHEBI:50924 DrugBank:DB00398 Drug_Central:2459 LINCS:LSM-1008 N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea sorafenib sorafenibum EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor drug liver toxicity Most-DILI-Concern