<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/TXPO?iri=http://purl.obolibrary.org/obo/CHEBI_60815"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0000056 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000056">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">participates in</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_32957 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_32957">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">lysophosphatidic acids</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_60815 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_60815">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">lysobisphosphatidic acid</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_32957"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000056"/>
                <allValuesFrom rdf:resource="http://purl.obolibrary.org/obo/TXPO_0000010"/>
            </Restriction>
        </rdfs:subClassOf>
        <ns4:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1&#39; of glycerol; and two additional fatty acids esterified to the glycerol head group.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BMP</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LBPA</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">bis(monoacylglycerol) hydrogen phosphate</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>BMP is a negatively charged phospholipid found almost exclusively in late endosomes/lysosomes.
BMP content is higher in alveolar macrophages (18% of total phospholipids) than in other cell types.

BMP is a structural isomer of phosphatidylglycerol (PG) and is synthesized through a series of acylation and deacylation steps involving a transacylase.
BMP its unusual sn-1;sn-1′ structural configuration (based on the phosphate-linked glycerol carbon), which is not observed in other phospholipids.
 This unusual configuration is thought to play a role in the resistance of BMP to many phospholipases, and its stability in late endosomes/lysosomes. BMP stimulates the degradation of glycosphingolipids in coordination with lipid binding proteins (saposins) in lysosomes.
PMID:25795792</oboInOwl:hasDbXref>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/TXPO_0000010 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0000010">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">changing membrane fluidity [Phospholipidosis]</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



