has role has attribute value has attribute antiviral drug organic molecular entity HIV fusion inhibitor maraviroc 4,4-difluoro-N-{(1S)-3-[(3-exo)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropyl}cyclohexanecarboxamide A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4,4-difluorocyclohexanecarboxylic acid and the primary amino group of (1S)-3-[(3-exo)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1-phenylpropylamine. An antiretroviral drug, it prevents the interaction of HIV-1 gp120 and chemokine receptor 5 (CCR5) necessary for CCR5-tropic HIV-1 to enter cells. CAS:376348-65-1 CHEBI:63608 DrugBank:DB04835 PMID:21134404 PMID:21383098 PMID:21393136 PMID:21505306 PMID:21595497 PMID:21692669 PMID:21987241 PMID:22017448 PMID:22034870 PMID:22064539 PMID:22090117 PMID:22118500 PMID:22174038 PMID:22236118 PMID:22247337 PMID:24419064 PMID:24651825 PMID:24652492 PMID:25017682 Reaxys:10131963 maraviroc maravirocum chemokine receptor 5 antagonist drug liver toxicity Most-DILI-Concern