has role has attribute value has attribute HIV protease inhibitor antiviral drug organic molecular entity tipranavir 3'-((1R)-1-((6R)-5,6-Dihydro-4-hydroxy-2-oxo-6-phenethyl-6-propyl-2H-pyran-3-yl)propyl)-5-(trifluoromethyl)-2-pyridinesulfonanilide A pyridine-2-sulfonamide substituted at C-5 by a trifluoromethyl group and at the sulfonamide nitrogen by a dihydropyrone-containing m-tolyl substituent. It is an HIV-1 protease inhibitor. CAS:174484-41-4 CHEBI:63628 DrugBank:DB00932 N-(3-{(1R)-1-[(6R)-4-hydroxy-2-oxo-6-(2-phenylethyl)-6-propyl-5,6-dihydro-2H-pyran-3-yl]propyl}phenyl)-5-(trifluoromethyl)pyridine-2-sulfonamide PMID:17620375 PMID:20368406 PMID:21041916 PMID:21571982 PMID:21576452 PMID:21825300 PMID:21871444 PMID:22007990 PMID:22096044 PMID:22258921 PMID:25017682 Reaxys:7698323 tipranavir drug liver toxicity Most-DILI-Concern