has role has attribute value has attribute antineoplastic agent tyrosine kinase inhibitor organic molecular entity angiogenesis modulating agent vascular endothelial growth factor receptor antagonist pazopanib 5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer. CAS:444731-52-6 CHEBI:71219 Drug_Central:4118 GW 78603 GW786034 LINCS:LSM-1114 PMID:21394443 PMID:21766486 PMID:21811833 PMID:22112314 PMID:22190407 PMID:22233389 PMID:22341567 PMID:22359392 PMID:22595799 PMID:22679111 PMID:22688250 PMID:22716487 PMID:22733110 PMID:22733795 PMID:22759480 PMID:22766517 PMID:22830347 PMID:22861374 PMID:22917595 PMID:22984765 PMID:23054212 PMID:23064954 PMID:23072642 PMID:23088634 PMID:23135778 Reaxys:11646488 pazopanib pazopanibum drug liver toxicity Most-DILI-Concern