has role has attribute value has attribute non-steroidal anti-inflammatory drug cyclooxygenase 2 inhibitor organic molecular entity lumiracoxib 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity. CAS:220991-20-8 CHEBI:73044 COX 189 COX-189 COX189 DrugBank:DB01283 Drug_Central:1618 PMID:14965322 PMID:15311562 PMID:15456339 PMID:17380211 PMID:19800190 PMID:21688392 PMID:22069133 PMID:22142375 PMID:22621454 PMID:22732767 Prexige Reaxys:9784107 lumiracoxib lumiracoxibum {2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid drug liver toxicity Most-DILI-Concern