has role has attribute value has attribute non-steroidal anti-inflammatory drug analgesic non-narcotic analgesic antipyretic EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor antineoplastic agent prodrug organic molecular entity tocolytic agent apoptosis inducer sulindac (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions. ATC:M01AB02 Beilstein:2951842 CAS:38194-50-2 CC1=C(CC(O)=O)c2cc(F)ccc2C\1=C/c1ccc(cc1)S(C)=O CHEBI:9352 Clinoril DrugBank:DB00605 Drug_Central:2534 PMID:11569947 PMID:11927004 PMID:12406542 PMID:15020200 PMID:15123337 PMID:19884509 PMID:23689354 PMID:23804703 Reaxys:2951842 Sulindac Sulindacum Wikipedia:Sulindac cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid sulindac sulindaco {(1Z)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid drug liver toxicity Most-DILI-Concern