has role has attribute value has attribute P450 inhibitor organic molecular entity EC 1.14.13.132 (squalene monooxygenase) inhibitor sterol biosynthesis inhibitor terbinafine (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections. CAS:91161-71-6 CHEBI:9448 DrugBank:DB00857 Drug_Central:2597 PMID:23750489 PMID:23802806 PMID:23841559 PMID:23895037 PMID:24126579 PMID:24352873 PMID:24389279 PMID:24410098 PMID:24447130 PMID:24452843 PMID:24477462 PMID:24490976 PMID:24497012 PMID:24533442 PMID:24563892 PMID:24576265 PMID:24581620 PMID:24588014 Reaxys:4256376 terbinafina terbinafine terbinafine terbinafinum drug liver toxicity Most-DILI-Concern