ground glass appearance [Liver Pathological Findings] Ground glass appearance [Liver PathologicalFindings] is a type of finding observed in hepatocyte cytoplasm. Based on the pathological morphology, lesions are observed as a frosted-like change in whole or most of the hepatocytes. Monochromatic eosinophilic change across the whole or most of the hepatocyte. It is often observed as a changing response to the hepatic metabolism enzyme inducer such as phenobarbital. In electron microscopy, it is regarded as prominent proliferation of smooth endoplasmic reticulum, dispersion of rough endoplasmic reticulum, with decrease of stored glycogen. Open TG-GatesID:FI-L0830 cytoplasmic alternation [Liver Pathological Findings]