GSTM3 (canonical)[Glutathione depletion] PMID:22496397 PMID:25202346 NCBI-Rat-GeneID:108348148 Six proteins were regulated at both basal and inducible levels exhibiting the largest dynamic range of Nrf2 regulation: cytochrome P4502A5 (CYP2A5; 17.2-fold), glutathione-S-transferase-Mu 3 (GSTM3; 6.4-fold), glutathione-S-transferase Mu 1 (GSTM1; 5.9-fold), ectonucleoside-triphosphate diphosphohydrolase (ENTPD5; 4.6-fold), UDP-glucose-6-dehydrogenase (UDPGDH; 4.1-fold) and epoxide hydrolase (EPHX1; 3.0-fold). These proteins, or their products, thus provide a potential source of biomarkers for Nrf2 activity. NCBI-Mouse-GeneID:14864 NCBI-Human-GeneID:2947 glutathione depletion dependent molecule (canonical) GSTM3 (mol)