relateds assay in vivo assay eosinogranular degeneration dependent molecule (mice) Acot3 (mouse)[Eosinophilic granular degeneration] PMID:28385385 NCBI-Mouse-GeneID:171281 ACOT3 is involved in the transport of DCAdicarboxylic acids into the peroxisomes by hydrolysis of long-medium chain fatty acyl-CoA esters to FFA, which can be further transported out of peroxisomes to mitochondria for beta-oxidation or excreted in the urinPMID:23359794 At the gene level, this was reflected by the up-regulation of cytochrome P450 (Cyp) 4a10, Cyp4a14, Cyp4a31 and Acyl-CoA thioesterase 3 (Acot3). Two relevant regulators, cytochrome P450 oxidoreductase (Por, rate limiting for cytochrome P450s) and the transcription factor constitutive androstane receptor (Car; official symbol Nr1i3) were also up-regulated in the quercetin-fed mice. Acot3 (mol)