has input has output has result has context has agent glutathione depletion [toxic course] NAPQI production glutathione depletion dependent process NAPQI [Glutathione depletion] NAPQI production [Glutathione depletion] NAPQI production is a subtype of generating a substance : A process that synthesizes NAPQI (N-acetyl-p-benzoquinone imine) as output. This entity is a specific course-dependent process. This process can constitute the course of Glutathione depletion. PMID:21177773 electrophiles formation [Glutathione depletion] Acetaminophen [Glutathione depletion] CYP2E1 (canonical)[Glutathione depletion] CYP3A4 (canonical)[Glutathione depletion] CYP1A2(canonical) [Glutathione depletion]