has participant has result has context glutathione depletion [toxic course] glutathione depletion dependent process JNK translocation from cytoplasm to mitochondria [Glutathione depletion] JNK translocation from cytoplasm to mitochondria is a subtype of transmitting: A process that of the directed movement of JNK from the cytoplasm to the mitochondria. This entity is a specific course-dependent process. This process can constitute the course of Glutathione depletion. chronic ethanol-induced activation of KCs is attributed to gut-sourced LPS, which is a major component of outer membrane of Gram-negative bacteria and passes through the intestinal epithelial barrier. Chronic ethanol exposure can increase translocation of LPS from gut to liver by enhancing the intestinal permeability and altering the gut microflora. JNK translocation from cytoplasm to mitochondria positive regulation of mitochondrial membrane permeability [Glutathione depletion] JNK (canonical)[Glutathione depletion]