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    <AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/description"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    


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    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">has part</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/TXPO_0000004 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/TXPO_0000004">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">has core process</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/TXPO_0000009 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0000009">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">toxic course</rdfs:label>
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    <Class rdf:about="http://purl.obolibrary.org/obo/TXPO_0000350">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cholestasis process [Cholestasis]</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/TXPO_0001277 -->

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        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cholestasis [toxic course]</rdfs:label>
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        <dc:description rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BSEP inhibition : bosentan, cyclosporin, glibenclamide, rifampicin, rifamycin</dc:description>
        <ns5:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The totality of all processes through which cholestasis is realized.</ns5:IAO_0000115>
        <rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">This entity is under construction.

Drug induced liver injury (DILI) is categorized as drug induced cholestasis (DIC), drug-induced hepatitis, and is mixed liver injury.
Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
phallodin, microsystin, amantin is facilitated by the uptake thpugh OATPs.
rifampicin, bosentan, troglitazone directly inhibit BSEP.</rdfs:comment>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">http://purl.bioontology.org/ontology/MEDDRA/10008635</oboInOwl:hasDbXref>
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